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Which sulfonamide is used topically?

Which sulfonamide is used topically? Sulfonamides available for topical use include silver sulfadiazine and mafenide burn cream, sulfanilamide vaginal cream and suppositories, and sulfacetamide ophthalmic.

What are short-acting antibiotics?

Short-acting oral antibiotics: penicillin V potassium, amoxillin (-clavulanate), cefacior, cefixime, cefuroxime, cefpodoxime proxetil, and cefprozil.

How do sulfonamides affect bacteria?

The sulfa drugs such as sulfonamides inhibit a critical enzyme–dihydropteroate synthase–in this process. Once the process is stopped, the bacteria can no longer grow. Another kind of antibiotic–tetracycline–also inhibits bacterial growth by stopping protein synthesis.

Are sulfonamides Antimetabolite antibacterial agents?

Sulfonamides are synthetic antibacterial compounds and are generally wide-spectrum drugs active against a range of bacterial species, both Gram-positive and Gram-negative.

Are sulfonamides Gram-positive or negative?

Sulfonamides are effective against Gram-positive and Gram-negative bacteria. Some protozoa, such as coccidians, Toxoplasma species and plasmodia, are generally sensitive. Chlamydia, Nocardia and Actinomyces species are also sensitive.

How long does short acting penicillin last?

When used to treat syphilis and certain other infections, this medication may cause a reaction that occurs several hours after starting treatment and can last up to 24 hours.

What type of antibiotic is co trimoxazole?

Co-trimoxazole is a combination of trimethoprim and sulfamethoxazole and is in a class of medications called sulfonamides. It works by stopping the growth of bacteria. Antibiotics will not kill viruses that can cause colds, flu, or other viral infections.

What is broad spectrum antibiotics?

The term « broad spectrum antibiotics » was originally used to designate antibiotics that were effective against both gram-positive and gram-negative bacteria, in contrast to penicillin, which is effective chiefly against gram-positive organisms, and streptomycin, which is active primarily against gram-negative bacteria.

How do sulfonamides destroy bacteria?

Sulfa drugs are bacteriostatic; i.e., they inhibit the growth and multiplication of bacteria but do not kill them. They act by interfering with the synthesis of folic acid (folate), a member of the vitamin B complex present in all living cells.

Are sulfonamides acidic or basic?

Cancerostatic aromatic sulfonamides 16-19 are generally weak acids with the acidity comparable or slightly lower than the lead sulfanilamide.

What is the action of sulfonamides?

Mechanism of Action

Sulfonamides competitively inhibit the incorporation of PABA into folic acid, thereby preventing the synthesis of folic acid. Trimethoprim binds reversibly to and inhibits dihyrofolate reductase, an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, decreasing folic acid synthesis.

Which drugs are sulphonamides?

Examples of sulfonamides includes sulfadiazine, sulfamethizole (brand name: Thiosulfil Forte), sulfamethoxazole (Gantanol), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin), and various high-strength combinations of three sulfonamides. Sulfa drugs kill bacteria and fungi by interfering with cell metabolism.

What are the indications of sulfonamides?

Sulfonamides, or « sulfa drugs, » are a group of medicines used to treat bacterial infections. They may be prescribed to treat urinary tract infections (UTIs), bronchitis, eye infections, bacterial meningitis, pneumonia, ear infections, severe burns, traveler’s diarrhea, and other conditions.

Why do sulfonamides cause Crystalluria?

The sulfa drugs are acetylated, primarily in the liver. The product is devoid of antimicrobial activity but retains the toxic potential to precipitate at neutral or acidic pH. This causes crystalluria and, therefore, potential damage to the kidney.

Are sulfonamides effective against gram-positive?

Sulfonamides are a class of antibiotics that are effective against many gram-positive bacteria and gram-negative bacteria. Some sulfonamides are applied directly to the skin (topically) to treat burns and skin, vaginal, and eye infections.

Why are sulfonamides bad?

Sulfonamides have the potential to cause a variety of untoward reactions, including urinary tract disorders, haemopoietic disorders, porphyria and hypersensitivity reactions. When used in large doses, they may cause a strong allergic reaction.

What is the fastest acting antibiotic?

Penicillin G sodium is a fast-acting antibiotic that fights bacteria in your body. Penicillin G sodium is used to treat many different types of severe infections, including strep infections, meningitis, anthrax, pneumonia, gonorrhea, and syphilis.

Is penicillin G semisynthetic?

Penicillins are bactericidal beta-lactam antibiotics that inhibit bacterial cell wall synthesis. A natural product, the penicillin structure has been modified to prepare a variety of semi-synthetic agents. The spectrum of antibacterial activity varies with each class of the penicillin family.

What is difference between penicillin G and penicillin?

Penicillin G benzathine, potassium, procaine and sodium are currently available in the United States in parenteral formulations for intravenous or intramuscular use. Penicillin V potassium (also called phenoxymethyl penicillin) is a more acid stable and can be administered orally.

What is the other name for cotrimoxazole?

Septrin is a brand name for a combination of antibiotics called cotrimoxazole. The same medication is available from other manufacturers with many different brand names, including Bactrim. Cotrimoxazole has two components: sulfamethoxazole and trimethoprim. Cotrimoxazole is a broad spectrum antibiotic.

Is co-trimoxazole a penicillin?

Co-trimoxazole is a combination antibiotic. It can be taken by people who are allergic to penicillin, but it is not suitable for people who are allergic to sulfonamides. Space out your doses evenly throughout the day, and remember to finish the course of treatment.

What is the other name for co-trimoxazole?

Trimethoprim/sulfamethoxazole (TMP/SMX), also known as co-trimoxazole among other names, is a combination antibiotic used to treat a variety of bacterial infections.

What are the 7 types of antibiotics?

7 Types of Antibiotics

  • Penicillins such as penicillin and amoxicillin.
  • Cephalosporins such as cephalexin (Keflex)
  • Macrolides such as erythromycin (E-Mycin), clarithromycin (Biaxin), and azithromycin (Zithromax)
  • Fluoroquinolones such as ciprofolxacin (Cipro), levofloxacin (Levaquin), and ofloxacin (Floxin)

Which drug is broad-spectrum?

Examples of broad-spectrum antibiotics

Aminoglycosides (except for streptomycin) Ampicillin. Amoxicillin/clavulanic acid (Augmentin) Azithromycin.

Is Penicillin G broad or narrow spectrum?

Penicillin G is a broad-spectrum, beta-lactam naturally occurring penicillin antibiotic with antibacterial activity. Penicillin G binds to and inactivates the penicillin binding proteins (PBPs) located inside the bacterial cell wall.



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